Varenzin™-CA1 for Cats & Dogs - Advanced Oral Therapy for Chronic Kidney Disease-Associated Anaemia

Varenzin™-CA1 for Cats & Dogs - Advanced Oral Therapy for Chronic Kidney Disease-Associated Anaemia

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Varenzin™-CA1 (Molidustat oral suspension) is a next-generation oral therapeutic formulated for cats and dogs suffering from anemia secondary to chronic kidney disease (CKD). By targeting the hypoxia-inducible factor (HIF) pathway, Varenzin™-CA1 helps stimulate endogenous erythropoietin (EPO) production, supporting healthy red blood cell formation without the need for injectable ESAs.

This therapy offers veterinarians and pet owners a convenient, non-injectable option to manage CKD-related anaemia, improving vitality, appetite, and overall quality of life in companion animals.
⭐ Key Benefits

🩸 Improves Anaemia in CKD - Supports red blood cell production in renal-compromised pets

💊 Oral Administration - No injections required; easy daily dosing

🐶🐱 Dual-Species Use - Suitable for both cats and dogs

⚙️ Physiologic Mechanism - Activates natural erythropoiesis via HIF stabilisation

🌿 Supports Energy & Vitality - Helps reduce lethargy and weakness associated with anaemia

🔬 Modern Renal Care Approach - Alternative or adjunct to erythropoietin therapy
💊 Usage & Dosage

Oral use only

May be given with or without food

Typical Starting Dosage (general guidance):

Cats

1-2 mg/kg once daily, adjusted based on response and laboratory monitoring

Dogs

1-3 mg/kg once daily, dosage individualised according to body weight, severity of anaemia, and veterinary assessment

📌 Important:

Regular monitoring of PCV/HCT, hemoglobin, and iron status is recommended

Dose adjustments should be made gradually based on clinical response
⚠️ Side Effects

Most pets tolerate Varenzin™-CA1 well. Potential side effects may include:

Mild gastrointestinal upset (vomiting, diarrhea)

Transient appetite changes

Increased blood pressure (rare; monitor in CKD patients)

Elevated hematocrit if overdosed

❗ Discontinue use and consult a veterinarian if signs of intolerance, excessive erythrocytosis, or adverse reactions occur.
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